Case study of a 3-year old girl with type 2 diabetes Monday, September 21, Tweet Washington: A case study of a 3-year old girl with type 2 diabetes — thought to be one of the youngest ever people to present with the condition — was recently presented at the annual meeting of the European Association for the Study of Diabetes in Stockholm, by Dr Michael Yafi, University of Texas Health Science Centre at Houston.
There was an increase in the frequency of gestational diabetes among women who had a history of infertility as illustrated in a study in the Indian Diabetic Clinic.
A prospective case control study in China inreported that a family history of diabetes greatly increased the incidence of GDM. This has been previously suggested by epidemiological studies in other populations, notably the Pima Indians[ 18 ] and in an animal model.
According to a study Canada, in December,one of the independent risk factors for development of GDM was previous unexplained neonatal deaths. The history of macrosomia in previous pregnancy was not found to be a risk factor for GDM, similar to another study.
A study reported that in patients with a history of GDM, the risk for recurrence increased if GDM was diagnosed earlier, as they required insulin, had elevated third-trimester plasma glucose level, and delivered macrosomic infants in their index pregnancy. To summarize, pre-pregnancy overweight and obesity, irregular menstrual cycle, history of treatment for infertility, family history of diabetes in first-degree relatives, history of diabetes in mother, history of previous pregnancy losses, past GDM, pre-maturity, pre-eclampsia, UTI, moniliasis, polyhydramnios, macrosomia, and pre-term labor were significantly associated with the presence of GDM in a univariate analysis.
In view of the above-mentioned findings, it is concluded that GDM is associated with several different modifiable and non-modifiable risk factors in our study.
As this was a hospital-based case control study, it could have been biased to a certain extent. Although increased parity is a known risk factor for GDM, it does not come as significant in our study. This might be due to the fact that hospital controls are often a source of selection bias.
Besides, the confounding effect of some other unknown factors may have a role to play. In spite of these constraints, the study provides valuable information, which can be helpful in planning maternal health services, by early identification and providing high quality prenatal care to GDM women.
Also screening of risk-pregnant patients will be cost-effective, especially in a developing country. We recommend that health authorities strengthen maternal health programs by focusing on the prevention and control of modifiable risk factors during the pre-pregnancy period and introducing corrective therapeutic interventions such as exercise and dietary modification.
Footnotes Conflict of Interest: None declared References 1. Gestational diabetes mellitus in India. J Assoc Physicians India. Foetal outcome in gestational diabetes in south Indians.
Diabetes Res Clin Pract. Characteristics of gestational diabetic mothers and their babies in an Indian diabetes clinic. An independent risk factor for gestational diabetes mellitus. Am J Obstet Gynecol. Diabetes and abnormal glucose tolerance in women with previous gestational diabetes.
The prevalence of gestational diabetes in a Sri Lankan antenatal clinic. Evaluation of the relationship between gestational diabetes and a history of polycystic ovarian syndrome.
Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women. Clin Endocrinol Oxf ; The prevalence of polycystic ovaries in women with a history of gestational diabetes. Prevalence of gestational diabetes mellitus and pregnancy outcomes in Asian women with polycystic ovary syndrome.
A prospective study of risk factors in pregnant women with abnormal glucose metabolism. A prospective study of pregravid determinants of gestational diabetes mellitus. Gestational diabetes in Iran: Incidence, risk factors and pregnancy outcomes.
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Washington: A case study of a 3-year old girl with type 2 diabetes — thought to be one of the youngest ever people to present with the condition — was recently presented at the annual meeting of the European Association for the Study of Diabetes in Stockholm, by Dr Michael Yafi, University of Texas Health Science Centre at Houston.
The purpose of this qualitative research case study was to evaluate the use of an integrative approach to address the multiple challenges posed by diabetes in India. The research design for the case study was based on the theoretical framework of participatory action research.
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